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CMap Candidate Details

Structure:
CMap ID: C04550
Pert ID: BRD-K70505054
Compound Name: ranitidine
Targets: HRH2
MoA: histamine receptor antagonist
SMILES: CN\C(NCCSCc1ccc(CN(C)C)o1)=C/[N+]([O-])=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4242 BRD-K70505054 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4473 BRD-K70505054 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4955 BRD-K70505054 VCAP 10 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
37725 BRD-K70505054 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37938 BRD-K70505054 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38544 BRD-K70505054 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38996 BRD-K70505054 SKB 10 uM 24 h 0.0 0.0 0.0 0.21 0.74 0.04
126652 BRD-K70505054 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126778 BRD-K70505054 JURKAT 3.33 uM 24 h 0.22 0.93 0.05 -0.4 -1.34 1.85
126840 BRD-K70505054 MCF??7.00 0.37 uM 24 h 0.29 1.22 0.48 0.0 0.0 0.0
126886 BRD-K70505054 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126914 BRD-K70505054 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126951 BRD-K70505054 THP1 0.04 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.73
134678 BRD-K70505054 A375 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134766 BRD-K70505054 HEK293 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134797 BRD-K70505054 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134826 BRD-K70505054 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134866 BRD-K70505054 HUVEC 0.03 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.62
134927 BRD-K70505054 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134990 BRD-K70505054 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).