CMap Candidate Details
Structure:
| CMap ID: | C04597 |
| Pert ID: | BRD-K02389548 |
| Compound Name: | RG2833 |
| Targets: | HDAC1|HDAC3 |
| MoA: | HDAC inhibitor |
| SMILES: | Cc1ccc(cc1)C(=O)NCCCCCC(=O)Nc1ccccc1N |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 122849 | BRD-K02389548 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122906 | BRD-K02389548 | HEK293 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.29 | 1.56 |
| 123031 | BRD-K02389548 | JURKAT | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.21 | -0.72 | 0.04 |
| 123121 | BRD-K02389548 | MDAMB231 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.27 | 0.95 | 0.32 |
| 123193 | BRD-K02389548 | THP1 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.0 | 0.55 |
| 131216 | BRD-K02389548 | A375 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131286 | BRD-K02389548 | HA1E | 2.22 uM | 24 h | -0.2 | -0.81 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131312 | BRD-K02389548 | HELA | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131329 | BRD-K02389548 | HT29 | 2.22 uM | 24 h | 0.19 | 0.81 | 0.0 | -0.26 | -0.86 | 0.21 |
| 131369 | BRD-K02389548 | HUVEC | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.25 | 0.9 | 0.21 |
| 131407 | BRD-K02389548 | MCF10A | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.89 | 0.26 |
| 131444 | BRD-K02389548 | MCF??7.00 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131468 | BRD-K02389548 | PC3 | 0.74 uM | 24 h | 0.19 | 0.79 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131506 | BRD-K02389548 | YAPC | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |