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CMap Candidate Details

Structure:
CMap ID: C04600
Pert ID: BRD-K56047318
Compound Name: RHC-80267
Targets: DAGLA|DAGLB
MoA: triacylglycerol lipase inhibitor
SMILES: O=C(NCCCCCCNC(=O)ON=C1CCCCC1)ON=C1CCCCC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2905 BRD-K56047318 HA1E 10 uM 24 h -0.22 -0.92 0.06 -0.28 -0.93 0.35
3380 BRD-K56047318 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3527 BRD-K56047318 PC3 10 uM 24 h -0.17 -0.73 0.0 0.0 0.0 0.0
3972 BRD-K56047318 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39147 BRD-K56047318 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39463 BRD-K56047318 A549 10 uM 6 h 0.0 0.0 0.0 0.25 0.89 0.21
39718 BRD-K56047318 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40020 BRD-K56047318 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.76
40293 BRD-K56047318 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40484 BRD-K56047318 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.63
40831 BRD-K56047318 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41137 BRD-K56047318 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41474 BRD-K56047318 SKB 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
99676 BRD-K56047318 U2OS 12.5 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).