CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00461
Pert ID:	BRD-K94830329
Compound Name:	ataluren
Targets:	DMD
MoA:	CFTR channel agonist; dystrophin stimulant
SMILES:	OC(=O)c1cccc(c1)-c1noc(n1)-c1ccccc1F
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
50438	BRD-K94830329	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
51081	BRD-K94830329	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128384	BRD-K94830329	A549	10 uM	24 h	0.27	1.14	0.31	0.0	0.0	0.0
128408	BRD-K94830329	HA1E	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128439	BRD-K94830329	HEK293	10 uM	24 h	0.0	0.0	0.0	-0.34	-1.15	1.07
128549	BRD-K94830329	JURKAT	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128641	BRD-K94830329	MDAMB231	3.33 uM	24 h	0.0	0.0	0.0	0.31	1.11	0.72
128682	BRD-K94830329	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128721	BRD-K94830329	THP1	10 uM	24 h	0.0	0.0	0.0	-0.37	-1.25	1.35
128767	BRD-K94830329	YAPC	0.37 uM	24 h	0.0	0.0	0.0	0.27	0.97	0.35
136181	BRD-K94830329	A375	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
136262	BRD-K94830329	HELA	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
136290	BRD-K94830329	HT29	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
136312	BRD-K94830329	MCF10A	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
136344	BRD-K94830329	MCF??7.00	2.22 uM	24 h	-0.18	-0.74	0.0	-0.28	-0.94	0.38

Summary