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CMap Candidate Details

Structure:
CMap ID: C04623
Pert ID: BRD-A75479906
Compound Name: rimantadine
Targets:
MoA: antiviral; RNA synthesis inhibitor
SMILES: CC(N)C12CC3CC(CC(C3)C1)C2
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
50311 BRD-A75479906 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51107 BRD-A75479906 VCAP 10 uM 6 h 0.27 1.11 0.25 -0.39 -1.32 1.71
90614 BRD-A75479906 HCT116 0.37 uM 24 h -0.17 -0.69 0.0 0.0 0.0 0.0
90685 BRD-A75479906 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.43
91419 BRD-A75479906 HUH7 20 uM 72 h 0.19 0.8 0.0 0.41 1.45 2.22
98060 BRD-A75479906 P1A82 0.125 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
127358 BRD-A75479906 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127396 BRD-A75479906 A549 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127432 BRD-A75479906 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127523 BRD-A75479906 JURKAT 0.37 uM 24 h 0.21 0.89 0.02 0.0 0.0 0.0
127577 BRD-A75479906 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.04
127613 BRD-A75479906 PC3 3.33 uM 24 h 0.26 1.07 0.19 0.28 1.01 0.44
127693 BRD-A75479906 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135372 BRD-A75479906 HELA 0.08 uM 24 h 0.24 1.01 0.12 0.0 0.0 0.0
135409 BRD-A75479906 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135501 BRD-A75479906 THP1 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).