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CMap Candidate Details

Structure:
CMap ID: C04634
Pert ID: BRD-K00317371
Compound Name: RITA
Targets: MDM2
MoA: MDM inhibitor
SMILES: OCc1ccc(s1)-c1ccc(o1)-c1ccc(CO)s1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1143 BRD-K00317371 A549 10 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.36
1343 BRD-K00317371 U2OS 10 uM 48 h 0.18 0.74 0.0 0.0 0.0 0.0
9629 BRD-K00317371 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10020 BRD-K00317371 HA1E 10 uM 6 h 0.0 0.0 0.0 0.31 1.08 0.65
10225 BRD-K00317371 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10429 BRD-K00317371 HCT116 10 uM 6 h 0.0 0.0 0.0 0.24 0.86 0.16
10702 BRD-K00317371 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10923 BRD-K00317371 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11257 BRD-K00317371 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11683 BRD-K00317371 NCIH508 10 uM 6 h 0.0 0.0 0.0 -0.43 -1.46 15.35
11951 BRD-K00317371 NCIH596 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.96 0.42
12234 BRD-K00317371 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12698 BRD-K00317371 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13177 BRD-K00317371 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13558 BRD-K00317371 VCAP 10 uM 6 h -0.26 -1.08 0.31 0.0 0.0 0.0
96058 BRD-K00317371 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96536 BRD-K00317371 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97247 BRD-K00317371 HAP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97365 BRD-K00317371 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).