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CMap Candidate Details

Structure:
CMap ID: C04641
Pert ID: BRD-K75699339
Compound Name: rizatriptan
Targets: HTR1A|HTR1B|HTR1D|HTR1E|HTR1F
MoA: serotonin receptor agonist
SMILES: CN(C)CCc1c[nH]c2ccc(Cn3cncn3)cc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5800 BRD-K75699339 HCC515 10 uM 6 h 0.0 0.0 0.0 0.35 1.24 1.28
5953 BRD-K75699339 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6588 BRD-K75699339 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24607 BRD-K75699339 A549 10 uM 24 h -0.25 -1.05 0.24 -0.33 -1.12 0.93
37733 BRD-K75699339 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38550 BRD-K75699339 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38774 BRD-K75699339 PHH 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 0.98
39000 BRD-K75699339 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127017 BRD-K75699339 A375 10 uM 24 h -0.26 -1.07 0.28 -0.36 -1.22 1.25
127041 BRD-K75699339 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 0.99
127065 BRD-K75699339 HEK293 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127097 BRD-K75699339 HELA 3.33 uM 24 h -0.18 -0.75 0.0 0.0 0.0 0.0
127207 BRD-K75699339 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127280 BRD-K75699339 THP1 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.07
127311 BRD-K75699339 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135146 BRD-K75699339 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135169 BRD-K75699339 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
135205 BRD-K75699339 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.37 1.32 1.71
135261 BRD-K75699339 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135298 BRD-K75699339 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).