CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04711
Pert ID:	BRD-K20714604
Compound Name:	RS-56812
Targets:	HTR3A
MoA:	serotonin receptor partial agonist
SMILES:	Cn1cc(C(=O)C(=O)N[C@H]2CN3CCC2CC3)c2ccccc12
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
2850	BRD-K20714604	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3161	BRD-K20714604	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3604	BRD-K20714604	PC3	10 uM	6 h	0.0	0.0	0.0	0.27	0.95	0.31
3948	BRD-K20714604	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
39102	BRD-K20714604	A375	10 uM	6 h	0.22	0.91	0.03	0.0	0.0	0.0
39308	BRD-K20714604	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
39647	BRD-K20714604	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
39963	BRD-K20714604	HEPG2	10 uM	6 h	0.22	0.91	0.04	0.27	0.94	0.3
40241	BRD-K20714604	HT29	10 uM	6 h	-0.17	-0.69	0.0	-0.32	-1.08	0.79
40598	BRD-K20714604	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.37	1.32	1.59
40770	BRD-K20714604	NEU	10 uM	24 h	0.25	1.04	0.14	0.31	1.09	0.67
41071	BRD-K20714604	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
41401	BRD-K20714604	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99737	BRD-K20714604	U2OS	10 uM	6 h	0.25	1.04	0.14	0.26	0.92	0.25

Summary