CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04736
Pert ID:	BRD-A65597028
Compound Name:	RX-821002
Targets:	ADRA1A\|ADRA1B\|ADRA1D\|ADRA2A\|ADRA2B\|ADRA2C
MoA:	adrenergic receptor antagonist
SMILES:	COC1(COc2ccccc2O1)C1=NCCN1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
6673	BRD-A65597028	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
7103	BRD-A65597028	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
7404	BRD-A65597028	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
7575	BRD-A65597028	HCC515	10 uM	6 h	0.0	0.0	0.0	-0.33	-1.11	0.9
7795	BRD-A65597028	HT29	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
8057	BRD-A65597028	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.25	0.88	0.19
8322	BRD-A65597028	PC3	10 uM	24 h	0.0	0.0	0.0	0.32	1.13	0.82
8608	BRD-A65597028	VCAP	10 uM	24 h	-0.22	-0.91	0.06	0.0	0.0	0.0
100275	BRD-A65597028	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary