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CMap Candidate Details

Structure:
CMap ID: C04767
Pert ID: BRD-K98453471
Compound Name: salirasib
Targets: TRPA1
MoA: mTOR inhibitor
SMILES: CC(C)=CCC\C(C)=C\CC\C(C)=C\CSc1ccccc1C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121806 BRD-K98453471 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121851 BRD-K98453471 PC3 10 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.13
129769 BRD-K98453471 A375 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129803 BRD-K98453471 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129847 BRD-K98453471 HEK293 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129880 BRD-K98453471 HELA 0.25 uM 24 h -0.24 -1.01 0.16 0.0 0.0 0.0
129926 BRD-K98453471 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
129972 BRD-K98453471 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130011 BRD-K98453471 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.06
130058 BRD-K98453471 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
130129 BRD-K98453471 THP1 0.03 uM 24 h 0.0 0.0 0.0 -0.21 -0.72 0.04
130172 BRD-K98453471 YAPC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).