CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04772
Pert ID:	BRD-K19284129
Compound Name:	salvinorin-a
Targets:	OPRD1\|OPRK1\|OPRM1
MoA:	opioid receptor agonist
SMILES:	COC(=O)[C@@H]1C[C@H](OC(C)=O)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)c1ccoc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
3156	BRD-K19284129	HCC515	10 uM	24 h	0.0	0.0	0.0	0.21	0.76	0.04
3741	BRD-K19284129	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
44542	BRD-K19284129	A549	10 uM	24 h	0.0	0.0	0.0	-0.21	-0.69	0.02
45194	BRD-K19284129	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.24	0.84	0.12
46327	BRD-K19284129	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46643	BRD-K19284129	SKB	10 uM	24 h	0.0	0.0	0.0	-0.34	-1.14	1.02
87904	BRD-K19284129	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
87961	BRD-K19284129	NPC	0.125 uM	24 h	0.0	0.0	0.0	-0.28	-0.96	0.42
120854	BRD-K19284129	A375	0.04 uM	24 h	0.0	0.0	0.0	0.23	0.83	0.11
120931	BRD-K19284129	HEK293	3.33 uM	24 h	0.0	0.0	0.0	0.3	1.07	0.62
121089	BRD-K19284129	YAPC	0.125 uM	24 h	0.0	0.0	0.0	-0.29	-0.99	0.5
129128	BRD-K19284129	HA1E	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129146	BRD-K19284129	HELA	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129180	BRD-K19284129	HT29	0.25 uM	24 h	-0.35	-1.44	1.43	-0.28	-0.94	0.37
129213	BRD-K19284129	PC3	0.03 uM	24 h	0.25	1.03	0.14	0.0	0.0	0.0

Summary