CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04796
Pert ID:	BRD-K77677632
Compound Name:	SB-200646
Targets:	HTR2B\|HTR2C
MoA:	serotonin receptor antagonist
SMILES:	Cn1ccc2cc(NC(=O)Nc3cccnc3)ccc12
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4142	BRD-K77677632	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
4488	BRD-K77677632	HCC515	10 uM	24 h	0.0	0.0	0.0	-0.33	-1.1	0.86
4720	BRD-K77677632	PC3	10 uM	24 h	-0.17	-0.72	0.0	0.28	0.99	0.39
4962	BRD-K77677632	VCAP	10 uM	24 h	0.21	0.86	0.01	0.38	1.34	1.72
39175	BRD-K77677632	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
39488	BRD-K77677632	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
40057	BRD-K77677632	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
40321	BRD-K77677632	HT29	10 uM	6 h	-0.27	-1.14	0.42	-0.46	-1.56	15.65
40504	BRD-K77677632	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.21	0.73	0.03
40865	BRD-K77677632	NEU	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
41182	BRD-K77677632	NPC	10 uM	24 h	0.3	1.26	0.56	0.0	0.0	0.0
41521	BRD-K77677632	SKB	10 uM	24 h	0.0	0.0	0.0	0.24	0.84	0.13
99498	BRD-K77677632	U2OS	10 uM	6 h	0.28	1.15	0.34	0.0	0.0	0.0

Summary