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CMap Candidate Details

Structure:
CMap ID: C04805
Pert ID: BRD-K61097567
Compound Name: SB-218795
Targets: TACR3
MoA: tachykinin antagonist
SMILES: COC(=O)[C@H](NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2914 BRD-K61097567 HA1E 10 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.07
3247 BRD-K61097567 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.86 0.2
3638 BRD-K61097567 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3847 BRD-K61097567 VCAP 10 uM 24 h -0.17 -0.72 0.0 0.0 0.0 0.0
41808 BRD-K61097567 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42119 BRD-K61097567 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42416 BRD-K61097567 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42733 BRD-K61097567 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43034 BRD-K61097567 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43214 BRD-K61097567 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43598 BRD-K61097567 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43901 BRD-K61097567 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44158 BRD-K61097567 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99719 BRD-K61097567 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).