CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04808
Pert ID:	BRD-K61323504
Compound Name:	SB-225002
Targets:	CXCR2
MoA:	CC chemokine receptor antagonist
SMILES:	Oc1cc(ccc1NC(=O)Nc1ccccc1Br)[N+]([O-])=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1762	BRD-K61323504	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
1931	BRD-K61323504	HCC515	10 uM	24 h	0.0	0.0	0.0	-0.19	-0.65	0.01
2481	BRD-K61323504	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
8963	BRD-K61323504	A375	12 uM	24 h	0.18	0.74	0.0	-0.41	-1.38	2.02
9464	BRD-K61323504	AGS	12 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
9771	BRD-K61323504	H1299	12 uM	6 h	0.0	0.0	0.0	-0.35	-1.18	1.14
10554	BRD-K61323504	HCT116	12 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
10815	BRD-K61323504	HEPG2	12 uM	6 h	-0.21	-0.87	0.02	-0.25	-0.82	0.15
10992	BRD-K61323504	HT29	12 uM	24 h	0.0	0.0	0.0	-0.29	-0.98	0.49
11222	BRD-K61323504	MCF??7.00	12 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
11530	BRD-K61323504	NCIH2073	12 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
11799	BRD-K61323504	NCIH508	12 uM	6 h	-0.17	-0.71	0.0	0.28	0.98	0.38
12093	BRD-K61323504	NCIH596	12 uM	6 h	0.0	0.0	0.0	-0.42	-1.41	2.02
12352	BRD-K61323504	NOMO1	12 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
12546	BRD-K61323504	PC3	12 uM	24 h	-0.24	-0.98	0.12	-0.24	-0.8	0.12
12830	BRD-K61323504	SW480	12 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
13073	BRD-K61323504	THP1	12 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
13317	BRD-K61323504	U937	12 uM	6 h	0.0	0.0	0.0	-0.39	-1.32	1.71
42120	BRD-K61323504	A549	10 uM	6 h	0.0	0.0	0.0	-0.3	-1.01	0.58
42417	BRD-K61323504	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
43599	BRD-K61323504	NPC	10 uM	24 h	0.22	0.91	0.03	-0.39	-1.3	1.57
43902	BRD-K61323504	PHH	10 uM	24 h	-0.21	-0.88	0.03	0.0	0.0	0.0
44159	BRD-K61323504	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99291	BRD-K61323504	U2OS	10 uM	6 h	0.0	0.0	0.0	-0.3	-1.02	0.6

Summary