CMap Candidate Details
Structure:
| CMap ID: | C04820 |
| Pert ID: | BRD-K41567364 |
| Compound Name: | SB-334867 |
| Targets: | HCRTR1|HCRTR2 |
| MoA: | orexin receptor antagonist |
| SMILES: | Cc1nc2ccc(NC(=O)Nc3ccnc4cccnc34)cc2o1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 4113 | BRD-K41567364 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 4573 | BRD-K41567364 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 4688 | BRD-K41567364 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 5084 | BRD-K41567364 | VCAP | 10 uM | 6 h | 0.23 | 0.96 | 0.08 | -0.29 | -0.99 | 0.51 |
| 44397 | BRD-K41567364 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 44705 | BRD-K41567364 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.32 | 1.15 | 0.88 |
| 44961 | BRD-K41567364 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 45256 | BRD-K41567364 | HEPG2 | 10 uM | 6 h | -0.23 | -0.98 | 0.12 | 0.0 | 0.0 | 0.0 |
| 45526 | BRD-K41567364 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 45696 | BRD-K41567364 | MCF??7.00 | 10 uM | 24 h | 0.23 | 0.98 | 0.09 | 0.0 | 0.0 | 0.0 |
| 46076 | BRD-K41567364 | NPC | 10 uM | 24 h | -0.2 | -0.84 | 0.01 | 0.0 | 0.0 | 0.0 |
| 46393 | BRD-K41567364 | PHH | 10 uM | 24 h | -0.24 | -1.0 | 0.15 | 0.0 | 0.0 | 0.0 |
| 46714 | BRD-K41567364 | SKB | 10 uM | 24 h | 0.24 | 0.99 | 0.1 | 0.39 | 1.37 | 2.02 |
| 99519 | BRD-K41567364 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.21 | 0.76 | 0.05 |