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CMap Candidate Details

Structure:
CMap ID: C04832
Pert ID: BRD-K24968862
Compound Name: SB-683698
Targets: ITGA4|ITGAV|ITGB1|ITGB7
MoA: integrin antagonist
SMILES: COc1cccc(OC)c1-c1ccc(C[C@H](NC(=O)c2c(Cl)cccc2Cl)C(O)=O)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95680 BRD-K24968862 U2OS 0.12 uM 48 h -0.26 -1.07 0.27 0.29 1.02 0.49
97288 BRD-K24968862 HAP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97353 BRD-K24968862 A375 3.33 uM 24 h 0.23 0.96 0.07 0.23 0.82 0.1
120919 BRD-K24968862 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120969 BRD-K24968862 HEK293 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121056 BRD-K24968862 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
121126 BRD-K24968862 YAPC 1.11 uM 24 h 0.19 0.79 0.0 0.0 0.0 0.0
129122 BRD-K24968862 A549 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129170 BRD-K24968862 HELA 2.22 uM 3 h -0.26 -1.09 0.33 0.0 0.0 0.0
129202 BRD-K24968862 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129228 BRD-K24968862 PC3 0.25 uM 24 h 0.0 0.0 0.0 -0.38 -1.29 1.53
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).