CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04903
Pert ID:	BRD-K49504902
Compound Name:	SEP-227900
Targets:	DAO
MoA:	D-Amino Acid Oxidase Inhibitor
SMILES:	OC(=O)c1cc2occc2[nH]1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
125600	BRD-K49504902	A375	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125686	BRD-K49504902	HELA	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125703	BRD-K49504902	HT29	10 uM	24 h	0.0	0.0	0.0	-0.3	-1.0	0.52
125758	BRD-K49504902	HUVEC	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125837	BRD-K49504902	MCF??7.00	3.33 uM	24 h	0.0	0.0	0.0	-0.32	-1.07	0.77
125883	BRD-K49504902	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125956	BRD-K49504902	YAPC	1.11 uM	24 h	0.4	1.68	1.65	0.0	0.0	0.0
133678	BRD-K49504902	A549	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133717	BRD-K49504902	HA1E	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133746	BRD-K49504902	HEK293	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133837	BRD-K49504902	JURKAT	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133872	BRD-K49504902	MCF10A	0.01 uM	24 h	0.0	0.0	0.0	0.27	0.97	0.35
133930	BRD-K49504902	MDAMB231	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133992	BRD-K49504902	THP1	0.08 uM	24 h	0.0	0.0	0.0	-0.4	-1.36	2.02

Summary