CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04907
Pert ID:	BRD-A95939040
Compound Name:	sertaconazole
Targets:
MoA:	sterol demethylase inhibitor
SMILES:	Clc1ccc(C(Cn2ccnc2)OCc2csc3c(Cl)cccc23)c(Cl)c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1857	BRD-A95939040	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
2531	BRD-A95939040	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
42248	BRD-A95939040	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
42585	BRD-A95939040	HEPG2	10 uM	6 h	0.33	1.37	0.97	0.37	1.32	1.61
43445	BRD-A95939040	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
43752	BRD-A95939040	PHH	10 uM	24 h	-0.3	-1.24	0.67	0.35	1.26	1.29
44037	BRD-A95939040	SKB	10 uM	24 h	0.29	1.19	0.42	0.0	0.0	0.0
91133	BRD-A95939040	HUH7	8 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
100417	BRD-A95939040	U2OS	4 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
128116	BRD-A95939040	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128146	BRD-A95939040	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128235	BRD-A95939040	MCF10A	0.125 uM	24 h	0.0	0.0	0.0	-0.23	-0.78	0.09
128266	BRD-A95939040	MCF??7.00	1.11 uM	24 h	0.0	0.0	0.0	-0.36	-1.22	1.24
128314	BRD-A95939040	MDAMB231	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128336	BRD-A95939040	PC3	10 uM	24 h	0.0	0.0	0.0	-0.17	-0.58	0.0
135819	BRD-A95939040	HA1E	0.25 uM	24 h	0.0	0.0	0.0	-0.24	-0.79	0.11
135859	BRD-A95939040	HEK293	2.22 uM	24 h	0.0	0.0	0.0	-0.26	-0.86	0.21
135950	BRD-A95939040	HT29	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135998	BRD-A95939040	JURKAT	2.22 uM	24 h	0.0	0.0	0.0	0.21	0.73	0.03
136096	BRD-A95939040	THP1	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
136144	BRD-A95939040	YAPC	0.74 uM	24 h	-0.17	-0.72	0.0	0.0	0.0	0.0

Summary