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CMap Candidate Details

Structure:
CMap ID: C04927
Pert ID: BRD-K98157055
Compound Name: SIB-1757
Targets: GRM5
MoA: glutamate receptor antagonist
SMILES: Cc1ccc(O)c(N=Nc2ccccc2)n1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3081 BRD-K98157055 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3419 BRD-K98157055 HCC515 10 uM 6 h 0.0 0.0 0.0 0.36 1.26 1.29
3578 BRD-K98157055 PC3 10 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.7
3997 BRD-K98157055 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.17 1.13
39255 BRD-K98157055 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39871 BRD-K98157055 ASC 10 uM 24 h -0.2 -0.83 0.0 0.0 0.0 0.0
40157 BRD-K98157055 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.3 1.05 0.57
40414 BRD-K98157055 HT29 10 uM 6 h 0.22 0.91 0.03 0.0 0.0 0.0
40555 BRD-K98157055 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40965 BRD-K98157055 NEU 10 uM 24 h -0.27 -1.12 0.39 0.35 1.22 1.18
41289 BRD-K98157055 NPC 10 uM 24 h 0.25 1.04 0.16 -0.34 -1.13 1.01
41634 BRD-K98157055 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).