CMap Candidate Details
Structure:
| CMap ID: | C04933 |
| Pert ID: | BRD-K80353138 |
| Compound Name: | silibinin |
| Targets: | ALOX5 |
| MoA: | cytochrome P450 inhibitor |
| SMILES: | COc1cc(ccc1O)[C@H]1Oc2cc(ccc2O[C@@H]1CO)[C@H]1Oc2cc(O)cc(O)c2C(=O)[C@@H]1O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 119664 | BRD-K80353138 | HEPG2 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 119702 | BRD-K80353138 | HT29 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.75 | 0.07 |
| 119750 | BRD-K80353138 | JURKAT | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.81 | 0.13 |
| 119790 | BRD-K80353138 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.9 | 0.28 |
| 119823 | BRD-K80353138 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.33 | 1.15 | 0.89 |