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CMap Candidate Details

Structure:
CMap ID: C04951
Pert ID: BRD-K19416115
Compound Name: sitagliptin
Targets: DPP4
MoA: dipeptidyl peptidase inhibitor
SMILES: N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
30389 BRD-K19416115 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
30990 BRD-K19416115 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31296 BRD-K19416115 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
32148 BRD-K19416115 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32377 BRD-K19416115 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32972 BRD-K19416115 SKB 10 uM 24 h 0.25 1.06 0.18 -0.28 -0.95 0.4
33257 BRD-K19416115 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95539 BRD-K19416115 A549 1.11 uM 6 h -0.22 -0.91 0.05 0.0 0.0 0.0
95677 BRD-K19416115 U2OS 0.12 uM 48 h 0.3 1.24 0.53 0.0 0.0 0.0
121361 BRD-K19416115 A375 1.11 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
121381 BRD-K19416115 HA1E 1.11 uM 24 h 0.2 0.82 0.0 -0.21 -0.69 0.03
121400 BRD-K19416115 HELA 1.11 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.64
121435 BRD-K19416115 HT29 1.11 uM 24 h 0.18 0.75 0.0 0.0 0.0 0.0
121457 BRD-K19416115 MCF??7.00 1.11 uM 24 h 0.18 0.75 0.0 0.0 0.0 0.0
121476 BRD-K19416115 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121501 BRD-K19416115 YAPC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).