CMap Candidate Details
Structure:
| CMap ID: | C05010 |
| Pert ID: | BRD-K24723746 |
| Compound Name: | solifenacin-succinate |
| Targets: | CHRM1|CHRM2|CHRM3|CHRM4|CHRM5 |
| MoA: | acetylcholine receptor antagonist |
| SMILES: | O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120871 | BRD-K24723746 | A375 | 10 uM | 24 h | -0.27 | -1.11 | 0.37 | 0.0 | 0.0 | 0.0 |
| 120889 | BRD-K24723746 | A549 | 10 uM | 24 h | 0.24 | 0.99 | 0.1 | 0.37 | 1.31 | 1.59 |
| 120963 | BRD-K24723746 | HEK293 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121052 | BRD-K24723746 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121120 | BRD-K24723746 | YAPC | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129141 | BRD-K24723746 | HA1E | 0.03 uM | 24 h | -0.24 | -0.98 | 0.13 | 0.0 | 0.0 | 0.0 |
| 129168 | BRD-K24723746 | HELA | 0.08 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129197 | BRD-K24723746 | HT29 | 0.01 uM | 24 h | -0.25 | -1.03 | 0.19 | 0.0 | 0.0 | 0.0 |
| 129223 | BRD-K24723746 | PC3 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |