CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05075
Pert ID:	BRD-K93880783
Compound Name:	stavudine
Targets:
MoA:	DNA directed DNA polymerase inhibitor; nucleoside reverse transcriptase inhibitor
SMILES:	Cc1cn([C@@H]2O[C@H](CO)C=C2)c(=O)[nH]c1=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
51197	BRD-K93880783	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
52214	BRD-K93880783	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
128103	BRD-K93880783	A375	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128130	BRD-K93880783	A549	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128207	BRD-K93880783	MCF10A	0.125 uM	24 h	0.24	1.0	0.11	0.0	0.0	0.0
128286	BRD-K93880783	MDAMB231	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128346	BRD-K93880783	THP1	1.11 uM	24 h	0.21	0.86	0.01	0.0	0.0	0.0
135796	BRD-K93880783	HA1E	0.01 uM	24 h	0.0	0.0	0.0	-0.28	-0.95	0.4
135841	BRD-K93880783	HEK293	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135881	BRD-K93880783	HELA	0.01 uM	24 h	0.0	0.0	0.0	-0.27	-0.9	0.29
135931	BRD-K93880783	HT29	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135970	BRD-K93880783	JURKAT	0.25 uM	24 h	-0.3	-1.23	0.63	-0.34	-1.13	0.98
136049	BRD-K93880783	PC3	0.01 uM	24 h	0.0	0.0	0.0	-0.45	-1.52	15.35
136116	BRD-K93880783	YAPC	0.01 uM	24 h	0.0	0.0	0.0	-0.3	-1.01	0.58

Summary