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CMap Candidate Details

Structure:
CMap ID: C05107
Pert ID: BRD-A70649075
Compound Name: sulconazole
Targets:
MoA: sterol demethylase inhibitor
SMILES: Clc1ccc(CSC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4025 BRD-A70649075 HA1E 10 uM 24 h 0.3 1.23 0.5 0.0 0.0 0.0
4316 BRD-A70649075 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
4624 BRD-A70649075 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5007 BRD-A70649075 VCAP 10 uM 6 h -0.17 -0.7 0.0 -0.35 -1.17 1.11
37097 BRD-A70649075 A375 10 uM 6 h -0.3 -1.24 0.67 0.0 0.0 0.0
37250 BRD-A70649075 A549 10 uM 24 h -0.27 -1.11 0.38 -0.32 -1.08 0.79
37541 BRD-A70649075 ASC 10 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.25
37846 BRD-A70649075 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38034 BRD-A70649075 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38164 BRD-A70649075 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38386 BRD-A70649075 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38657 BRD-A70649075 PHH 10 uM 24 h 0.29 1.2 0.42 0.0 0.0 0.0
38883 BRD-A70649075 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100304 BRD-A70649075 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).