CMap Candidate Details
Structure:
| CMap ID: | C05155 |
| Pert ID: | BRD-K75911534 |
| Compound Name: | SU014813 |
| Targets: | KDR |
| MoA: | PDGFR tyrosine kinase receptor inhibitor; VEGFR inhibitor |
| SMILES: | Cc1[nH]c(\C=C2\C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 127044 | BRD-K75911534 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127066 | BRD-K75911534 | HEK293 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127101 | BRD-K75911534 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127139 | BRD-K75911534 | HT29 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127165 | BRD-K75911534 | JURKAT | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.19 | 0.67 | 0.01 |
| 127182 | BRD-K75911534 | MCF10A | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.07 | 0.64 |
| 127210 | BRD-K75911534 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127239 | BRD-K75911534 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127283 | BRD-K75911534 | THP1 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.08 | 0.79 |
| 127314 | BRD-K75911534 | YAPC | 10 uM | 24 h | -0.28 | -1.18 | 0.51 | 0.33 | 1.17 | 0.93 |
| 135017 | BRD-K75911534 | A375 | 2.22 uM | 24 h | -0.28 | -1.16 | 0.46 | 0.0 | 0.0 | 0.0 |
| 135043 | BRD-K75911534 | A549 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135266 | BRD-K75911534 | MDAMB231 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |