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CMap Candidate Details

Structure:
CMap ID: C05169
Pert ID: BRD-K63516691
Compound Name: T-0156
Targets: PDE5A
MoA: phosphodiesterase inhibitor
SMILES: COC(=O)c1c(-c2cc(OC)c(OC)c(OC)c2)c2ccnc(OCc3ncccn3)c2c(=O)n1Cc1ccnc(C)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2915 BRD-K63516691 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
3249 BRD-K63516691 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
3639 BRD-K63516691 PC3 10 uM 6 h 0.0 0.0 0.0 -0.45 -1.53 15.35
3849 BRD-K63516691 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
39156 BRD-K63516691 A375 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.82
39336 BRD-K63516691 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39731 BRD-K63516691 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40028 BRD-K63516691 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40300 BRD-K63516691 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40842 BRD-K63516691 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41149 BRD-K63516691 NPC 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.45 15.35
41487 BRD-K63516691 SKB 10 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.23
97916 BRD-K63516691 MCF??7.00 3.33 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99319 BRD-K63516691 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).