CMap Candidate Details
Structure:
| CMap ID: | C05191 |
| Pert ID: | BRD-K58501140 |
| Compound Name: | TAK-875 |
| Targets: | FFAR1 |
| MoA: | insulin secretagogue |
| SMILES: | Cc1cc(OCCCS(C)(=O)=O)cc(C)c1-c1cccc(COc2ccc3[C@H](CC(O)=O)COc3c2)c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 123516 | BRD-K58501140 | A375 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123566 | BRD-K58501140 | HEK293 | 10 uM | 24 h | 0.25 | 1.02 | 0.13 | -0.35 | -1.18 | 1.14 |
| 123616 | BRD-K58501140 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123642 | BRD-K58501140 | HT29 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.4 | -1.35 | 2.02 |
| 123683 | BRD-K58501140 | MCF10A | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123723 | BRD-K58501140 | MCF??7.00 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.94 | 0.39 |
| 123742 | BRD-K58501140 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123761 | BRD-K58501140 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.89 | 0.26 |
| 132008 | BRD-K58501140 | HA1E | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.89 | 0.26 |