CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05200
Pert ID:	BRD-A94276798
Compound Name:	talinolol
Targets:	ADRB1
MoA:	adrenergic receptor antagonist
SMILES:	CC(C)(C)NCC(O)COc1ccc(NC(=O)NC2CCCCC2)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
128381	BRD-A94276798	A549	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128436	BRD-A94276798	HEK293	0.37 uM	24 h	0.0	0.0	0.0	0.3	1.07	0.64
128477	BRD-A94276798	HELA	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128546	BRD-A94276798	JURKAT	3.33 uM	24 h	0.24	1.01	0.12	-0.37	-1.25	1.35
128593	BRD-A94276798	MCF10A	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128608	BRD-A94276798	MCF??7.00	0.125 uM	24 h	0.0	0.0	0.0	0.3	1.06	0.59
128638	BRD-A94276798	MDAMB231	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128680	BRD-A94276798	PC3	10 uM	24 h	-0.19	-0.81	0.0	0.0	0.0	0.0
128718	BRD-A94276798	THP1	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128765	BRD-A94276798	YAPC	10 uM	24 h	0.21	0.87	0.01	0.0	0.0	0.0
136178	BRD-A94276798	A375	0.03 uM	24 h	0.0	0.0	0.0	-0.38	-1.28	1.45
136223	BRD-A94276798	HA1E	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
136288	BRD-A94276798	HT29	0.08 uM	24 h	0.0	0.0	0.0	0.27	0.97	0.35

Summary