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CMap Candidate Details

Structure:
CMap ID: C05201
Pert ID: BRD-K75615183
Compound Name: talipexole
Targets: ADRA2A|DRD2|HTR3A
MoA: adrenergic receptor agonist; dopamine receptor agonist
SMILES: Nc1nc2CCN(CC=C)CCc2s1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3050 BRD-K75615183 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3256 BRD-K75615183 HCC515 10 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
3641 BRD-K75615183 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3979 BRD-K75615183 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39174 BRD-K75615183 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39343 BRD-K75615183 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39761 BRD-K75615183 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40054 BRD-K75615183 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40319 BRD-K75615183 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40503 BRD-K75615183 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40862 BRD-K75615183 NEU 10 uM 24 h -0.25 -1.05 0.23 -0.27 -0.92 0.33
41518 BRD-K75615183 SKB 10 uM 24 h 0.0 0.0 0.0 0.45 1.59 2.37
99466 BRD-K75615183 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).