CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05234
Pert ID:	BRD-K81062487
Compound Name:	taurocholate
Targets:	CEL\|FABP6\|SLCO1C1
MoA:	G protein-coupled receptor agonist
SMILES:	C[C@H](CCC(=O)NCCS(O)(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
33612	BRD-K81062487	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
33844	BRD-K81062487	A549	10 uM	24 h	0.0	0.0	0.0	-0.26	-0.87	0.23
34183	BRD-K81062487	ASC	10 uM	24 h	0.0	0.0	0.0	-0.32	-1.07	0.75
34425	BRD-K81062487	HA1E	10 uM	6 h	-0.31	-1.3	0.82	-0.29	-0.98	0.47
34690	BRD-K81062487	HCC515	10 uM	6 h	-0.18	-0.76	0.0	-0.31	-1.05	0.7
34968	BRD-K81062487	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.23	0.83	0.12
35207	BRD-K81062487	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
35416	BRD-K81062487	MCF??7.00	10 uM	6 h	0.23	0.97	0.08	0.0	0.0	0.0
36104	BRD-K81062487	PC3	10 uM	6 h	0.0	0.0	0.0	0.29	1.03	0.51
36356	BRD-K81062487	PHH	10 uM	24 h	0.0	0.0	0.0	-0.33	-1.1	0.86
36654	BRD-K81062487	SKB	10 uM	24 h	-0.22	-0.93	0.07	-0.28	-0.93	0.35
37005	BRD-K81062487	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
91456	BRD-K81062487	HUH7	6.66 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
99094	BRD-K81062487	NEU	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
99252	BRD-K81062487	NPC	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary