CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05279
Pert ID:	BRD-K81376179
Compound Name:	TCS-359
Targets:	FLT3
MoA:	FLT3 inhibitor
SMILES:	COc1ccc(cc1OC)C(=O)Nc1sc2CCCCc2c1C(N)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
6803	BRD-K81376179	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
7030	BRD-K81376179	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
7358	BRD-K81376179	HA1E	10 uM	24 h	-0.22	-0.9	0.04	0.25	0.89	0.2
7718	BRD-K81376179	HCC515	10 uM	6 h	0.24	1.0	0.11	0.0	0.0	0.0
8026	BRD-K81376179	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
8113	BRD-K81376179	MCF??7.00	10 uM	24 h	-0.21	-0.87	0.02	0.0	0.0	0.0
8846	BRD-K81376179	VCAP	10 uM	6 h	0.0	0.0	0.0	-0.39	-1.32	1.71
97215	BRD-K81376179	PC3	10 uM	24 h	0.0	0.0	0.0	-0.23	-0.78	0.1

Summary