CMap Candidate Details
Structure:
| CMap ID: | C05282 |
| Pert ID: | BRD-A13964793 |
| Compound Name: | TC1 |
| Targets: | BACE1 |
| MoA: | beta-secretase inhibitor |
| SMILES: | OC12C3C4C5C3C(C3C5CC4C13)N2CCc1cccc(F)c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 4156 | BRD-A13964793 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 4512 | BRD-A13964793 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 4979 | BRD-A13964793 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 37326 | BRD-A13964793 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 37444 | BRD-A13964793 | ASC | 10 uM | 24 h | -0.24 | -0.98 | 0.12 | -0.39 | -1.32 | 1.71 |
| 37786 | BRD-A13964793 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 37983 | BRD-A13964793 | HT29 | 10 uM | 6 h | -0.22 | -0.9 | 0.04 | 0.29 | 1.02 | 0.48 |
| 38296 | BRD-A13964793 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 38820 | BRD-A13964793 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95570 | BRD-A13964793 | MCF??7.00 | 10 uM | 48 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.85 | 0.2 |
| 95662 | BRD-A13964793 | U2OS | 10 uM | 48 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96595 | BRD-A13964793 | A375 | 10 uM | 24 h | -0.24 | -0.98 | 0.13 | 0.0 | 0.0 | 0.0 |
| 96668 | BRD-A13964793 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.84 | 0.13 |