CMap Candidate Details
Structure:
| CMap ID: | C05284 |
| Pert ID: | BRD-K06900071 |
| Compound Name: | tebipenem |
| Targets: | CNR1 |
| MoA: | bacterial cell wall synthesis inhibitor |
| SMILES: | C[C@@H](O)[C@@H]1[C@@H]2[C@H](C)C(SC3CN(C3)C3=NCCS3)=C(N2C1=O)C(=O)OCOC(=O)C(C)(C)C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 122550 | BRD-K06900071 | A375 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.78 | 0.09 |
| 122682 | BRD-K06900071 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122726 | BRD-K06900071 | MCF10A | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.1 | 0.86 |
| 122775 | BRD-K06900071 | MDAMB231 | 10 uM | 24 h | 0.27 | 1.13 | 0.29 | 0.27 | 0.96 | 0.34 |
| 122796 | BRD-K06900071 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.94 | 0.38 |
| 130886 | BRD-K06900071 | A549 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130918 | BRD-K06900071 | HA1E | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.38 | 1.35 | 1.72 |
| 130938 | BRD-K06900071 | HEK293 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130971 | BRD-K06900071 | HELA | 2.22 uM | 24 h | 0.21 | 0.86 | 0.01 | 0.0 | 0.0 | 0.0 |
| 131048 | BRD-K06900071 | HUVEC | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.17 | 1.13 |
| 131085 | BRD-K06900071 | MCF??7.00 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.16 | 1.1 |
| 131187 | BRD-K06900071 | YAPC | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |