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CMap Candidate Details

Structure:
CMap ID: C05288
Pert ID: BRD-K59436580
Compound Name: tedizolid
Targets:
MoA: bacterial 50S ribosomal subunit inhibitor
SMILES: Cn1nnc(n1)-c1ccc(cn1)-c1ccc(cc1F)N1C[C@H](CO)OC1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123809 BRD-K59436580 A375 0.125 uM 24 h -0.28 -1.17 0.48 0.0 0.0 0.0
123850 BRD-K59436580 A549 1.11 uM 24 h 0.19 0.8 0.0 0.0 0.0 0.0
123917 BRD-K59436580 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123970 BRD-K59436580 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124019 BRD-K59436580 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124070 BRD-K59436580 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124101 BRD-K59436580 MCF??7.00 10 uM 24 h -0.21 -0.9 0.04 -0.27 -0.92 0.32
124137 BRD-K59436580 MDAMB231 3.33 uM 24 h -0.27 -1.12 0.38 0.0 0.0 0.0
124200 BRD-K59436580 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124253 BRD-K59436580 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132174 BRD-K59436580 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132205 BRD-K59436580 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132308 BRD-K59436580 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.49
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).