CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05303
Pert ID:	BRD-K73999723
Compound Name:	telmisartan
Targets:	AGTR1\|PPARG
MoA:	angiotensin receptor antagonist
SMILES:	CCCc1nc2c(C)cc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1nc2ccccc2n1C
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4481	BRD-K73999723	HCC515	10 uM	24 h	0.0	0.0	0.0	-0.28	-0.95	0.41
25534	BRD-K73999723	VCAP	10 uM	6 h	0.0	0.0	0.0	-0.26	-0.89	0.26
40053	BRD-K73999723	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
41178	BRD-K73999723	NPC	10 uM	24 h	0.0	0.0	0.0	0.31	1.1	0.68
41516	BRD-K73999723	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
91492	BRD-K73999723	HUH7	6.66 uM	72 h	0.21	0.87	0.01	0.22	0.79	0.07
95304	BRD-K73999723	A549	10 uM	24 h	0.0	0.0	0.0	-0.29	-0.96	0.44
95460	BRD-K73999723	U2OS	1.11 uM	6 h	0.0	0.0	0.0	-0.26	-0.87	0.22
97124	BRD-K73999723	A375	10 uM	24 h	0.2	0.82	0.0	0.0	0.0	0.0
97192	BRD-K73999723	PC3	10 uM	24 h	0.0	0.0	0.0	0.36	1.28	1.42
127428	BRD-K73999723	HA1E	3.33 uM	24 h	0.0	0.0	0.0	0.24	0.85	0.14
127467	BRD-K73999723	HELA	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127519	BRD-K73999723	JURKAT	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127576	BRD-K73999723	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127689	BRD-K73999723	YAPC	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135406	BRD-K73999723	HT29	2.22 uM	24 h	0.0	0.0	0.0	-0.31	-1.04	0.66
135440	BRD-K73999723	MCF10A	0.74 uM	24 h	0.0	0.0	0.0	0.29	1.02	0.47
135500	BRD-K73999723	THP1	2.22 uM	24 h	0.0	0.0	0.0	-0.33	-1.12	0.94

Summary