CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05334
Pert ID:	BRD-A06352418
Compound Name:	terfenadine
Targets:	CHRM1\|CHRM2\|CHRM3\|CHRM4\|CHRM5\|HRH1\|KCNH1\|KCNH2
MoA:	histamine receptor antagonist
SMILES:	CC(C)(C)c1ccc(cc1)C(O)CCCN1CCC(CC1)C(O)(c1ccccc1)c1ccccc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5142	BRD-A06352418	A375	10 uM	6 h	-0.19	-0.78	0.0	0.0	0.0	0.0
5385	BRD-A06352418	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
5490	BRD-A06352418	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
6231	BRD-A06352418	PC3	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
6353	BRD-A06352418	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
37322	BRD-A06352418	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
37433	BRD-A06352418	ASC	10 uM	24 h	0.27	1.13	0.29	0.0	0.0	0.0
37780	BRD-A06352418	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
37974	BRD-A06352418	HT29	10 uM	6 h	0.0	0.0	0.0	0.37	1.31	1.59
38125	BRD-A06352418	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	-0.41	-1.36	2.02
38287	BRD-A06352418	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38596	BRD-A06352418	PHH	10 uM	24 h	0.0	0.0	0.0	0.23	0.8	0.08
38812	BRD-A06352418	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
91056	BRD-A06352418	HUH7	6.66 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary