CMap Candidate Details
Structure:
| CMap ID: | C05336 |
| Pert ID: | BRD-A42699921 |
| Compound Name: | teriflunomide |
| Targets: | DHODH |
| MoA: | dihydroorotate dehydrogenase inhibitor |
| SMILES: | CC(=O)C(C#N)C(=O)Nc1ccc(cc1)C(F)(F)F |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 87992 | BRD-A42699921 | A549 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.37 | -1.26 | 1.35 |
| 88035 | BRD-A42699921 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121579 | BRD-A42699921 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121625 | BRD-A42699921 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121694 | BRD-A42699921 | YAPC | 10 uM | 24 h | 0.25 | 1.02 | 0.13 | -0.32 | -1.07 | 0.77 |
| 129574 | BRD-A42699921 | A375 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.06 | 0.72 |
| 129621 | BRD-A42699921 | HT29 | 0.03 uM | 24 h | 0.16 | 0.65 | 0.0 | 0.3 | 1.06 | 0.58 |
| 129673 | BRD-A42699921 | PC3 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |