CMap Candidate Details
Structure:
| CMap ID: | C05371 |
| Pert ID: | BRD-K39841531 |
| Compound Name: | TG-101209 |
| Targets: | JAK2|JAK3 |
| MoA: | JAK inhibitor |
| SMILES: | CN1CCN(CC1)c1ccc(Nc2ncc(C)c(Nc3cccc(c3)S(=O)(=O)NC(C)(C)C)n2)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 96627 | BRD-K39841531 | A375 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.74 | 0.05 |
| 96695 | BRD-K39841531 | PC3 | 3.33 uM | 24 h | 0.21 | 0.9 | 0.02 | -0.3 | -1.0 | 0.52 |
| 118724 | BRD-K39841531 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.22 | 0.76 | 0.05 |
| 118761 | BRD-K39841531 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 118800 | BRD-K39841531 | HCC515 | 0.12 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.2 | 0.69 | 0.01 |
| 118842 | BRD-K39841531 | HEPG2 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 118885 | BRD-K39841531 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 118925 | BRD-K39841531 | MCF??7.00 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |