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CMap Candidate Details

Structure:
CMap ID: C05421
Pert ID: BRD-K00603606
Compound Name: ticlopidine
Targets: P2RY12
MoA: purinergic receptor antagonist
SMILES: Clc1ccccc1CN1CCc2sccc2C1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5567 BRD-K00603606 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
5873 BRD-K00603606 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6507 BRD-K00603606 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37114 BRD-K00603606 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37574 BRD-K00603606 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38413 BRD-K00603606 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38678 BRD-K00603606 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38902 BRD-K00603606 SKB 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.29 1.52
91060 BRD-K00603606 HUH7 12.5 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
122881 BRD-K00603606 HEK293 3.33 uM 24 h 0.0 0.0 0.0 -0.41 -1.38 2.02
122933 BRD-K00603606 HELA 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123006 BRD-K00603606 JURKAT 1.11 uM 24 h -0.25 -1.03 0.2 -0.31 -1.06 0.73
123054 BRD-K00603606 MCF10A 0.125 uM 24 h 0.32 1.33 0.85 -0.23 -0.76 0.07
123095 BRD-K00603606 MDAMB231 3.33 uM 24 h 0.28 1.19 0.41 0.0 0.0 0.0
123167 BRD-K00603606 THP1 3.33 uM 24 h -0.27 -1.11 0.36 -0.27 -0.92 0.32
131232 BRD-K00603606 A549 0.01 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
131272 BRD-K00603606 HA1E 0.25 uM 24 h 0.28 1.17 0.38 -0.37 -1.25 1.35
131322 BRD-K00603606 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131343 BRD-K00603606 HUVEC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131427 BRD-K00603606 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131455 BRD-K00603606 PC3 0.08 uM 24 h -0.24 -0.99 0.13 0.29 1.02 0.49
131485 BRD-K00603606 YAPC 0.01 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).