CMap Candidate Details
Structure:
| CMap ID: | C05445 |
| Pert ID: | BRD-A10039652 |
| Compound Name: | tipranavir |
| Targets: | |
| MoA: | HIV protease inhibitor |
| SMILES: | CCC[C@@]1(CCc2ccccc2)CC(=O)C([C@H](CC)c2cccc(NS(=O)(=O)c3ccc(cn3)C(F)(F)F)c2)C(=O)O1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121157 | BRD-A10039652 | A375 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121194 | BRD-A10039652 | A549 | 0.37 uM | 24 h | 0.24 | 1.0 | 0.1 | -0.25 | -0.83 | 0.17 |
| 121227 | BRD-A10039652 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121323 | BRD-A10039652 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.32 | 1.14 | 0.87 |
| 129278 | BRD-A10039652 | HELA | 0.74 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129306 | BRD-A10039652 | HT29 | 2.22 uM | 24 h | -0.3 | -1.23 | 0.64 | -0.24 | -0.79 | 0.11 |
| 129341 | BRD-A10039652 | MCF??7.00 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.97 | 0.45 |
| 129378 | BRD-A10039652 | YAPC | 0.03 uM | 24 h | 0.21 | 0.89 | 0.02 | 0.2 | 0.71 | 0.02 |