CMap Candidate Details
Structure:
| CMap ID: | C05495 |
| Pert ID: | BRD-K91822704 |
| Compound Name: | torcitabine |
| Targets: | DCK|TK2 |
| MoA: | DNA polymerase inhibitor |
| SMILES: | Nc1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 127351 | BRD-K91822704 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.31 | 1.1 | 0.69 |
| 127391 | BRD-K91822704 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127423 | BRD-K91822704 | HA1E | 10 uM | 24 h | 0.17 | 0.73 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127464 | BRD-K91822704 | HELA | 3.33 uM | 24 h | 0.21 | 0.86 | 0.01 | 0.38 | 1.33 | 1.72 |
| 127514 | BRD-K91822704 | JURKAT | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.87 | 0.23 |
| 127573 | BRD-K91822704 | MCF??7.00 | 10 uM | 24 h | -0.18 | -0.77 | 0.0 | -0.29 | -0.98 | 0.49 |
| 127606 | BRD-K91822704 | PC3 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.35 | 1.25 | 1.29 |
| 127684 | BRD-K91822704 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135401 | BRD-K91822704 | HT29 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 1.0 | 0.42 |
| 135438 | BRD-K91822704 | MCF10A | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.1 | 0.88 |
| 135497 | BRD-K91822704 | THP1 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.22 | 0.77 | 0.06 |