CMap Candidate Details
Structure:
| CMap ID: | C05500 |
| Pert ID: | BRD-A41450521 |
| Compound Name: | tosufloxacin |
| Targets: | |
| MoA: | bacterial DNA gyrase inhibitor |
| SMILES: | NC1CCN(C1)c1nc2n(cc(C(O)=O)c(=O)c2cc1F)-c1ccc(F)cc1F |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24382 | BRD-A41450521 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24529 | BRD-A41450521 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24721 | BRD-A41450521 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24842 | BRD-A41450521 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.06 | 0.74 |
| 25218 | BRD-A41450521 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.07 | 0.75 |
| 25292 | BRD-A41450521 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 51672 | BRD-A41450521 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91227 | BRD-A41450521 | HUH7 | 8 uM | 72 h | -0.21 | -0.88 | 0.03 | -0.23 | -0.78 | 0.09 |