CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05535
Pert ID:	BRD-K71879491
Compound Name:	tretinoin
Targets:	ALDH1A1\|ALDH1A2\|GPRC5A\|NR0B1\|NR2C2\|PPARD\|RARA\|RARB\|RARG\|RARRES1\|RORB\|RORC\|RXRB\|RXRG
MoA:	retinoid receptor agonist; retinoid receptor ligand
SMILES:	CC(/C=C/C1=C(C)CCCC1(C)C)=C\C=C\C(C)=C\C(O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
993	BRD-K71879491	CD34	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
1052	BRD-K71879491	HL60	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
1114	BRD-K71879491	U937	3.33 uM	6 h	-0.27	-1.12	0.39	0.0	0.0	0.0
1131	BRD-K71879491	MCF??7.00	0.37 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
1137	BRD-K71879491	PC3	2.22 uM	6 h	0.21	0.88	0.01	-0.31	-1.04	0.66
1449	BRD-K71879491	NPC	1.67 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
34165	BRD-K71879491	ASC	10 uM	24 h	-0.26	-1.08	0.3	0.3	1.07	0.63
36334	BRD-K71879491	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
36631	BRD-K71879491	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
36861	BRD-K71879491	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
53325	BRD-K71879491	MCF10A	10 uM	24 h	0.22	0.91	0.04	0.0	0.0	0.0
90969	BRD-K71879491	HUH7	12 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
99081	BRD-K71879491	NEU	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
111495	BRD-K71879491	U2OS	20 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
115969	BRD-K71879491	A375	10 uM	24 h	0.22	0.93	0.05	0.0	0.0	0.0
116008	BRD-K71879491	A549	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
116047	BRD-K71879491	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
116090	BRD-K71879491	HCC515	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
116134	BRD-K71879491	HEPG2	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
116181	BRD-K71879491	HT29	0.37 uM	24 h	0.0	0.0	0.0	-0.33	-1.12	0.93

Summary