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CMap Candidate Details

Structure:
CMap ID: C05551
Pert ID: BRD-K68202742
Compound Name: trichostatin-a
Targets: HDAC1|HDAC10|HDAC2|HDAC3|HDAC4|HDAC5|HDAC6|HDAC7|HDAC8|HDAC9
MoA: HDAC inhibitor
SMILES: C[C@H](\C=C(C)\C=C\C(=O)NO)C(=O)c1ccc(cc1)N(C)C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25835 BRD-K68202742 A375 10 uM 6 h 0.0 0.0 0.0 0.3 1.05 0.58
26751 BRD-K68202742 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27996 BRD-K68202742 NEU 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.48
28309 BRD-K68202742 NPC 10 uM 24 h 0.22 0.94 0.06 -0.33 -1.11 0.92
28676 BRD-K68202742 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
28942 BRD-K68202742 PHH 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.35
29277 BRD-K68202742 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
29521 BRD-K68202742 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
30233 BRD-K68202742 A549 10 uM 6 h -0.24 -1.0 0.15 0.23 0.8 0.08
30526 BRD-K68202742 ASC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.09 0.85
31111 BRD-K68202742 HCC515 10 uM 6 h 0.0 0.0 0.0 0.33 1.18 0.97
31422 BRD-K68202742 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31777 BRD-K68202742 HT29 10 uM 6 h 0.0 0.0 0.0 0.24 0.84 0.13
90588 BRD-K68202742 MCF??7.00 0.37 uM 6 h 0.0 0.0 0.0 -0.23 -0.77 0.08
90842 BRD-K68202742 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97263 BRD-K68202742 HAP1 0.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
111486 BRD-K68202742 U2OS 20 uM 6 h -0.26 -1.1 0.34 0.0 0.0 0.0
136396 BRD-K68202742 SHSY5Y 0.04 uM 24 h 0.25 1.05 0.17 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).