CMap Candidate Details
Structure:
| CMap ID: | C05560 |
| Pert ID: | BRD-K03243820 |
| Compound Name: | trifluridine |
| Targets: | TYMS |
| MoA: | DNA directed DNA polymerase inhibitor; thymidylate synthase inhibitor |
| SMILES: | OC[C@H]1O[C@H](C[C@@H]1O)n1cc(c(=O)[nH]c1=O)C(F)(F)F |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 52260 | BRD-K03243820 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95489 | BRD-K03243820 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.27 | 0.95 | 0.32 |
| 95605 | BRD-K03243820 | MCF??7.00 | 10 uM | 6 h | 0.28 | 1.16 | 0.36 | 0.0 | 0.0 | 0.0 |
| 95710 | BRD-K03243820 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 98557 | BRD-K03243820 | NEU | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 98626 | BRD-K03243820 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.14 | 1.01 |