CMap Candidate Details
Structure:
| CMap ID: | C05601 |
| Pert ID: | BRD-K83776863 |
| Compound Name: | tryptophan |
| Targets: | CASR|IDO1|SLC36A1|WARS|WARS2 |
| MoA: | serotonin receptor partial agonist |
| SMILES: | N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 52694 | BRD-K83776863 | A549 | 6.66 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 52724 | BRD-K83776863 | HEPG2 | 20 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.37 | -1.24 | 1.31 |
| 53126 | BRD-K83776863 | MCF10A | 100 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.84 | 0.13 |