CMap Candidate Details
Structure:
| CMap ID: | C05619 |
| Pert ID: | BRD-K76064317 |
| Compound Name: | tyrphostin-AG-1296 |
| Targets: | FLT3 |
| MoA: | FLT3 inhibitor |
| SMILES: | COc1cc2ncc(nc2cc1OC)-c1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1622 | BRD-K76064317 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2121 | BRD-K76064317 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2288 | BRD-K76064317 | PC3 | 10 uM | 24 h | -0.17 | -0.73 | 0.0 | 0.31 | 1.08 | 0.66 |
| 2774 | BRD-K76064317 | VCAP | 10 uM | 6 h | -0.24 | -1.01 | 0.17 | 0.0 | 0.0 | 0.0 |
| 41978 | BRD-K76064317 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 42468 | BRD-K76064317 | ASC | 10 uM | 24 h | -0.24 | -0.99 | 0.13 | 0.25 | 0.9 | 0.22 |
| 42778 | BRD-K76064317 | HEPG2 | 10 uM | 6 h | -0.22 | -0.91 | 0.05 | 0.0 | 0.0 | 0.0 |
| 43072 | BRD-K76064317 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 43233 | BRD-K76064317 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.27 | 1.39 |
| 43646 | BRD-K76064317 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.22 | 1.24 |
| 43945 | BRD-K76064317 | PHH | 10 uM | 24 h | 0.22 | 0.94 | 0.05 | 0.0 | 0.0 | 0.0 |
| 97161 | BRD-K76064317 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 99473 | BRD-K76064317 | U2OS | 20 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |