CMap Candidate Details
Structure:
| CMap ID: | C05622 |
| Pert ID: | BRD-K34533029 |
| Compound Name: | tyrphostin-AG-494 |
| Targets: | EGFR |
| MoA: | EGFR inhibitor |
| SMILES: | Oc1ccc(cc1O)\C=C(/C#N)C(=O)Nc1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1583 | BRD-K34533029 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 1916 | BRD-K34533029 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2394 | BRD-K34533029 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.23 | 0.82 | 0.1 |
| 2487 | BRD-K34533029 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 41766 | BRD-K34533029 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 42091 | BRD-K34533029 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 42354 | BRD-K34533029 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 42680 | BRD-K34533029 | HEPG2 | 10 uM | 6 h | -0.27 | -1.14 | 0.43 | 0.0 | 0.0 | 0.0 |
| 42984 | BRD-K34533029 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 43186 | BRD-K34533029 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.21 | 1.24 |
| 43545 | BRD-K34533029 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 43843 | BRD-K34533029 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 44110 | BRD-K34533029 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.29 | 1.03 | 0.5 |