CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05636
Pert ID:	BRD-K70281171
Compound Name:	U-99194
Targets:	DRD3
MoA:	dopamine receptor antagonist
SMILES:	CCCN(CCC)C1Cc2cc(OC)c(OC)cc2C1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
2918	BRD-K70281171	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3253	BRD-K70281171	HCC515	10 uM	24 h	0.2	0.83	0.0	0.29	1.01	0.45
3536	BRD-K70281171	PC3	10 uM	24 h	0.26	1.09	0.24	0.0	0.0	0.0
3978	BRD-K70281171	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
39166	BRD-K70281171	A375	10 uM	6 h	0.0	0.0	0.0	-0.34	-1.15	1.07
39479	BRD-K70281171	A549	10 uM	6 h	-0.29	-1.19	0.55	-0.16	-0.54	0.0
39751	BRD-K70281171	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
40044	BRD-K70281171	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
40311	BRD-K70281171	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
40497	BRD-K70281171	MCF??7.00	10 uM	24 h	0.29	1.21	0.47	-0.31	-1.04	0.68
40853	BRD-K70281171	NEU	10 uM	24 h	0.0	0.0	0.0	-0.24	-0.8	0.12
41168	BRD-K70281171	NPC	10 uM	24 h	0.0	0.0	0.0	-0.19	-0.63	0.0
41506	BRD-K70281171	SKB	10 uM	24 h	-0.2	-0.84	0.01	-0.25	-0.86	0.2
99404	BRD-K70281171	U2OS	10 uM	6 h	0.0	0.0	0.0	-0.23	-0.76	0.07

Summary