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CMap Candidate Details

Structure:
CMap ID: C05640
Pert ID: BRD-A45499626
Compound Name: UBP-296
Targets: GRIK1
MoA: glutamate receptor antagonist
SMILES: NC(Cn1ccc(=O)n(Cc2ccccc2C(O)=O)c1=O)C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2808 BRD-A45499626 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.96 0.43
3317 BRD-A45499626 HCC515 10 uM 6 h 0.0 0.0 0.0 0.24 0.86 0.16
3439 BRD-A45499626 PC3 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
3925 BRD-A45499626 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44246 BRD-A45499626 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44646 BRD-A45499626 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44768 BRD-A45499626 ASC 10 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
45088 BRD-A45499626 HEPG2 10 uM 6 h -0.25 -1.03 0.2 -0.35 -1.18 1.14
45363 BRD-A45499626 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45744 BRD-A45499626 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45887 BRD-A45499626 NPC 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.11
46203 BRD-A45499626 PHH 10 uM 24 h 0.22 0.9 0.03 0.0 0.0 0.0
46518 BRD-A45499626 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100174 BRD-A45499626 U2OS 10 uM 6 h 0.15 0.63 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).